Constitutive Expression of Interleukin (IL)-4 In Vivo Causes Autoimmune-type Disorders in Mice

The transgenic (tg) expression of interleukin (IL)-4 under the control of a major histocompatibility complex (MHC) class I promoter leads to B cell hyperactivity in mice, characterized by increased B cell surface MHC class II and CD23 expression, elevated responsiveness of the B cells to polyclonal...

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Detalles Bibliográficos
Autores principales: Erb, Klaus J., Rüger, Beate, von Brevern, Maja, Ryffel, Bernhard, Schimpl, Annelise, Rivett, Karen
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196114/
https://www.ncbi.nlm.nih.gov/pubmed/9016881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196114/
https://www.ncbi.nlm.nih.gov/pubmed/9016881

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