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Peripheral Expression of Jak3 Is Required to Maintain T Lymphocyte Function

The Jak family tyrosine kinase, Jak3, is involved in signaling through cytokine receptors that utilize the common γ chain (γ(c)), such as those for IL-2, IL-4, IL-7, IL-9, and IL-15. Recent studies of Jak3-deficient mice and humans have demonstrated that Jak3 plays a critical role in B and T lymphoc...

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Detalles Bibliográficos
Autores principales: Thomis, Daniel C., Berg, Leslie J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196115/
https://www.ncbi.nlm.nih.gov/pubmed/9016869

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