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Negative Selection in the Thymus Includes Semimature T Cells
The thymic medulla plays a key role in negative selection (self-tolerance induction) and contains differentiated T cells en route to the extrathymic environment. However, being relatively mature, medullary T cells are thought to be beyond the stage of tolerance induction. This paradox is resolved by...
Autores principales: | Kishimoto, Hidehiro, Sprent, Jonathan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196120/ https://www.ncbi.nlm.nih.gov/pubmed/9016875 |
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