Absence of Respiratory Burst in X-linked Chronic Granulomatous Disease Mice Leads to Abnormalities in Both Host Defense and Inflammatory Response to Aspergillus fumigatus

Mice with X-linked chronic granulomatous disease (CGD) generated by targeted disruption of the gp91(phox) subunit of the NADPH–oxidase complex (X-CGD mice) were examined for their response to respiratory challenge with Aspergillus fumigatus. This opportunistic fungal pathogen causes infection in CGD...

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Autores principales: Morgenstern, David E., Gifford, Mary A.C., Li, Ling Lin, Doerschuk, Claire M., Dinauer, Mary C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196125/
https://www.ncbi.nlm.nih.gov/pubmed/9016870

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