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Mouse Ly-49A Interrupts Early Signaling Events in Natural Killer Cell Cytotoxicity and Functionally Associates with the SHP-1 Tyrosine Phosphatase
The lytic activity of natural killer (NK) cells is inhibited by the expression of class I major histocompatibility complex (MHC) antigens on target cells. In murine NK cells, Ly-49A mediates inhibition of cytotoxicity in response to the class I MHC antigen H-2D(d). In this report, we studied the fun...
Autores principales: | Nakamura, Mary C., Niemi, Eréne C., Fisher, Mark J., Shultz, Leonard D., Seaman, William E., Ryan, James C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196152/ https://www.ncbi.nlm.nih.gov/pubmed/9034146 |
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