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Role of the Multiple T Cell Receptor (TCR)-ζ Chain Signaling Motifs in Selection of the T Cell Repertoire
Immature thymocytes undergo a selection process within the thymus based on their T cell antigen receptor (TCR) specificity that results either in their maturation into functionally competent, self-MHC–restricted T cells (positive selection) or their deletion (negative selection). The outcome of thym...
Autores principales: | Shores, Elizabeth W., Tran, Tom, Grinberg, Alexander, Sommers, Connie L., Shen, Howard, Love, Paul E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196173/ https://www.ncbi.nlm.nih.gov/pubmed/9120395 |
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