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Role of PI 3-kinase, Akt and Bcl-2–related proteins in sustaining the survival of neurotrophic factor–independent adult sympathetic neurons

By adulthood, sympathetic neurons have lost dependence on NGF and NT-3 and are able to survive in culture without added neurotrophic factors. To understand the molecular mechanisms that sustain adult neurons, we established low density, glial cell-free cultures of 12-wk rat superior cervical ganglio...

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Detalles Bibliográficos
Autores principales:	Orike, Nina, Middleton, Gayle, Borthwick, Emma, Buchman, Vladimir, Cowen, Timothy, Davies, Alun M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2001
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196191/ https://www.ncbi.nlm.nih.gov/pubmed/11524433 http://dx.doi.org/10.1083/jcb.200101068

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