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Collagen-induced Arthritis Is Reduced in 5-Lipoxygenase-activating Protein-deficient Mice

Collagen-induced arthritis in the DBA/1 mouse is an experimental model of human rheumatoid arthritis. To examine the role of leukotrienes in the pathogenesis of this disease, we have developed embryonic stem (ES) cells from this mouse strain. Here, we report that DBA/1 mice made deficient in 5-lipox...

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Detalles Bibliográficos
Autores principales: Griffiths, Richard J., Smith, MaryAlice, Roach, Marsha L., Stock, Jeffrey L., Stam, Ethan J., Milici, A.J., Scampoli, Deborah N., Eskra, James D., Byrum, Robert S., Koller, Beverly H., McNeish, John D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196231/
https://www.ncbi.nlm.nih.gov/pubmed/9091585

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