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Light Chain Usage in Anti–double-stranded DNA B Cell Subsets: Role in Cell Fate Determination
Two major mechanisms for the regulation of autoreactive B cells that arise in the bone marrow are functional silencing (anergy) and deletion. Studies to date suggest that low avidity interactions between B cells and autoantigen lead to B cell silencing, whereas high avidity interactions lead to dele...
Autores principales: | Spatz, Linda, Saenko, Vladimir, Iliev, Andrey, Jones, Lori, Geskin, Larisa, Diamond, Betty |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196257/ https://www.ncbi.nlm.nih.gov/pubmed/9104818 |
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