Intracellular Antimicrobial Activity in the Absence of Interferon-γ: Effect of Interleukin-12 in Experimental Visceral Leishmaniasis in Interferon-γ Gene-disrupted Mice

Despite permitting uncontrolled intracellular visceral infection for 8 wk, interferon-γ (IFN-γ) gene knockout (GKO) mice infected with Leishmania donovani proceeded to reduce liver parasite burdens by 50% by week 12. This late-developing IFN-γ–independent antileishmanial mechanism appeared to be dep...

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Detalles Bibliográficos
Autores principales: Taylor, Alice P., Murray, Henry W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196266/
https://www.ncbi.nlm.nih.gov/pubmed/9104810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196266/
https://www.ncbi.nlm.nih.gov/pubmed/9104810

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