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Suppression of Herpes Simplex Virus Type 1 (HSV-1)–induced Pneumonia in Mice by Inhibition of Inducible Nitric Oxide Synthase (iNOS, NOS2)

Intranasal Herpes simplex virus type 1 (HSV-1) infection of mice caused pneumonia. Manifestations of the disease included: histological pneumonitis, pulmonary influx of lymphocytes, decreased pulmonary compliance, and decreased survival. Immunohistochemical staining demonstrated iNOS induction and t...

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Detalles Bibliográficos
Autores principales: Adler, Heiko, Beland, Janice L., Del-Pan, Nadia C., Kobzik, Lester, Brewer, Joanne P., Martin, Thomas R., Rimm, Ilonna J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196291/
https://www.ncbi.nlm.nih.gov/pubmed/9151890