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Spermine Inhibits Proinflammatory Cytokine Synthesis in Human Mononuclear Cells: A Counterregulatory Mechanism that Restrains the Immune Response
The local production of proinflammatory cytokines mediates the host response to inflammation, infection, and injury, whereas an overexpression of these mediators can injure or kill the host. Recently, we identified a class of multivalent guanylhydrazone compounds that are effective inhibitors of pro...
Autores principales: | Zhang, Minghuang, Caragine, Theresa, Wang, Haichao, Cohen, Pamela S., Botchkina, Galina, Soda, Kuniyasu, Bianchi, Marina, Ulrich, Peter, Cerami, Anthony, Sherry, Barbara, Tracey, Kevin J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196317/ https://www.ncbi.nlm.nih.gov/pubmed/9151701 |
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