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Degradation of T Cell Receptor (TCR)–CD3-ζ Complexes after Antigenic Stimulation
T cell activation by specific antigen results in a rapid and long-lasting downregulation of triggered T cell receptors (TCRs). In this work, we investigated the fate of downregulated TCR– CD3-ζ complexes. T cells stimulated by peptide-pulsed antigen-presenting cells (APCs) undergo an antigen dose-de...
Autores principales: | Valitutti, Salvatore, Müller, Sabina, Salio, Mariolina, Lanzavecchia, Antonio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196323/ https://www.ncbi.nlm.nih.gov/pubmed/9151711 |
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