Interleukin-5 Expression in the Lung Epithelium of Transgenic Mice Leads to Pulmonary Changes Pathognomonic of Asthma

We have generated transgenic mice that constitutively express murine interleukin (IL)-5 in the lung epithelium. Airway expression of this cytokine resulted in a dramatic accumulation of peribronchial eosinophils and striking pathologic changes including the expansion of bronchusassociated lymphoid t...

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Detalles Bibliográficos
Autores principales: Lee, James J., McGarry, Michael P., Farmer, Steven C., Denzler, Karen L., Larson, Kirsten A., Carrigan, Patricia E., Brenneise, Ina E., Horton, Margaret A., Haczku, Angela, Gelfand, Erwin W., Leikauf, George D., Lee, Nancy A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196351/
https://www.ncbi.nlm.nih.gov/pubmed/9182686

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