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CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding

To study the role of CD8β in T cell function, we derived a CD8α/β(−) (CD8(−/−)) T cell hybridoma of the H-2K(d)–restricted N9 cytotoxic T lymphocyte clone specific for a photoreactive derivative of the Plasmodium berghei circumsporozoite peptide PbCS 252-260. This hybridoma was transfected either wi...

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Detalles Bibliográficos
Autores principales: Renard, Valery, Romero, Pedro, Vivier, Eric, Malissen, Bernard, Luescher, Immanuel F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196369/
https://www.ncbi.nlm.nih.gov/pubmed/8976201