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Lineage Commitment in the Thymus: Only the Most Differentiated (TCR(hi)bcl-2(hi)) Subset of CD4(+)CD8(+)Thymocytes Has Selectively Terminated CD4 or CD8 Synthesis
Lineage commitment is a developmental process by which individual CD4(+)CD8(+) (double positive, DP) thymocytes make a decision to differentiate into either CD4(+) or CD8(+) T cells. However, the molecular event(s) that defines lineage commitment is controversial. We have previously proposed that li...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1996
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196385/ https://www.ncbi.nlm.nih.gov/pubmed/8976166 |