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High resolution mapping of mast cell membranes reveals primary and secondary domains of FcεRI and LAT

In mast cells, cross-linking the high-affinity IgE receptor (FcεRI) initiates the Lyn-mediated phosphorylation of receptor ITAMs, forming phospho-ITAM binding sites for Syk. Previous immunogold labeling of membrane sheets showed that resting FcεRI colocalize loosely with Lyn, whereas cross-linked Fc...

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Detalles Bibliográficos
Autores principales:	Wilson, Bridget S., Pfeiffer, Janet R., Surviladze, Zurab, Gaudet, Elizabeth A., Oliver, Janet M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2001
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196429/ https://www.ncbi.nlm.nih.gov/pubmed/11489921 http://dx.doi.org/10.1083/jcb.200104049

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