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Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation
Recent studies indicate that insulin stimulation of glucose transporter (GLUT)4 translocation requires at least two distinct insulin receptor–mediated signals: one leading to the activation of phosphatidylinositol 3 (PI-3) kinase and the other to the activation of the small GTP binding protein TC10....
Autores principales: | Watson, Robert T., Shigematsu, Satoshi, Chiang, Shian-Huey, Mora, Silvia, Kanzaki, Makoto, Macara, Ian G., Saltiel, Alan R., Pessin, Jeffrey E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196453/ https://www.ncbi.nlm.nih.gov/pubmed/11502760 http://dx.doi.org/10.1083/jcb.200102078 |
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