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Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation
Keratins 8 and 18 belong to the keratin family of intermediate filament (IF) proteins and constitute a hallmark for all simple epithelia, including the liver. Hepatocyte IFs are made solely of keratins 8 and 18 (K8/K18). In these cells, the loss of one partner via a targeted null mutation in the ger...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196458/ https://www.ncbi.nlm.nih.gov/pubmed/11514590 http://dx.doi.org/10.1083/jcb.200102130 |