Disruption of cytoskeletal integrity impairs G(i)-mediated signaling due to displacement of G(i) proteins

β1 integrins play a crucial role as cytoskeletal anchorage proteins. In this study, the coupling of the cytoskeleton and intracellular signaling pathways was investigated in β1 integrin deficient (−/−) embryonic stem cells. Muscarinic inhibition of the L-type Ca(2+) current (I(Ca)) and activation of...

Descripción completa

Detalles Bibliográficos
Autores principales: Bloch, Wilhelm, Fan, Yun, Han, Ji, Xue, Sheng, Schöneberg, Torsten, Ji, Guanju, Lu, Zhong J., Walther, Michael, Fässler, Reinhard, Hescheler, Jürgen, Addicks, Klaus, Fleischmann, Bernd K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196465/
https://www.ncbi.nlm.nih.gov/pubmed/11514589
http://dx.doi.org/10.1083/jcb.200103011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196465/
https://www.ncbi.nlm.nih.gov/pubmed/11514589
http://dx.doi.org/10.1083/jcb.200103011

Ejemplares similares