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Disruption of cytoskeletal integrity impairs G(i)-mediated signaling due to displacement of G(i) proteins

β1 integrins play a crucial role as cytoskeletal anchorage proteins. In this study, the coupling of the cytoskeleton and intracellular signaling pathways was investigated in β1 integrin deficient (−/−) embryonic stem cells. Muscarinic inhibition of the L-type Ca(2+) current (I(Ca)) and activation of...

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Detalles Bibliográficos
Autores principales:	Bloch, Wilhelm, Fan, Yun, Han, Ji, Xue, Sheng, Schöneberg, Torsten, Ji, Guanju, Lu, Zhong J., Walther, Michael, Fässler, Reinhard, Hescheler, Jürgen, Addicks, Klaus, Fleischmann, Bernd K.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2001
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196465/ https://www.ncbi.nlm.nih.gov/pubmed/11514589 http://dx.doi.org/10.1083/jcb.200103011

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