Nuclear pore complexes: dynamics in unexpected places

In vivo studies on the dynamics of the nuclear pore complex (NPC) in yeast suggested that NPCs are highly mobile in the nuclear envelope. However, new evidence indicates that in mammalian cells NPCs are stably attached to a flexible lamina framework, but a peripheral component can exchange rapidly w...

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Detalles Bibliográficos
Autores principales: Lyman, Susan K., Gerace, Larry
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196851/
https://www.ncbi.nlm.nih.gov/pubmed/11448985
http://dx.doi.org/10.1083/jcb.200106071
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author Lyman, Susan K.
Gerace, Larry
author_facet Lyman, Susan K.
Gerace, Larry
author_sort Lyman, Susan K.
collection PubMed
description In vivo studies on the dynamics of the nuclear pore complex (NPC) in yeast suggested that NPCs are highly mobile in the nuclear envelope. However, new evidence indicates that in mammalian cells NPCs are stably attached to a flexible lamina framework, but a peripheral component can exchange rapidly with an intranuclear pool.
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spelling pubmed-21968512008-05-01 Nuclear pore complexes: dynamics in unexpected places Lyman, Susan K. Gerace, Larry J Cell Biol Reviews In vivo studies on the dynamics of the nuclear pore complex (NPC) in yeast suggested that NPCs are highly mobile in the nuclear envelope. However, new evidence indicates that in mammalian cells NPCs are stably attached to a flexible lamina framework, but a peripheral component can exchange rapidly with an intranuclear pool. The Rockefeller University Press 2001-07-09 /pmc/articles/PMC2196851/ /pubmed/11448985 http://dx.doi.org/10.1083/jcb.200106071 Text en Copyright © 2001, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Reviews
Lyman, Susan K.
Gerace, Larry
Nuclear pore complexes: dynamics in unexpected places
title Nuclear pore complexes: dynamics in unexpected places
title_full Nuclear pore complexes: dynamics in unexpected places
title_fullStr Nuclear pore complexes: dynamics in unexpected places
title_full_unstemmed Nuclear pore complexes: dynamics in unexpected places
title_short Nuclear pore complexes: dynamics in unexpected places
title_sort nuclear pore complexes: dynamics in unexpected places
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196851/
https://www.ncbi.nlm.nih.gov/pubmed/11448985
http://dx.doi.org/10.1083/jcb.200106071
work_keys_str_mv AT lymansusank nuclearporecomplexesdynamicsinunexpectedplaces
AT geracelarry nuclearporecomplexesdynamicsinunexpectedplaces

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