Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p

Cell cycle progression is driven by waves of cyclin expression coupled with regulated protein degradation. An essential step for initiating mitosis is the inactivation of proteolysis mediated by the anaphase-promoting complex/cyclosome (APC/C) bound to its regulator Cdh1p/Hct1p. Yeast APC(Cdh1) was...

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Detalles Bibliográficos
Autores principales: Huang, James N., Park, Iha, Ellingson, Eric, Littlepage, Laurie E., Pellman, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196868/
https://www.ncbi.nlm.nih.gov/pubmed/11448992
http://dx.doi.org/10.1083/jcb.200102007

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