Deletion of Murine SMN Exon 7 Directed to Skeletal Muscle Leads to Severe Muscular Dystrophy

Spinal muscular atrophy (SMA) is characterized by degeneration of motor neurons of the spinal cord associated with muscle paralysis and caused by mutations of the survival motor neuron gene (SMN). To determine whether SMN gene defect in skeletal muscle might have a role in SMA pathogenesis, deletion...

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Detalles Bibliográficos
Autores principales: Cifuentes-Diaz, Carmen, Frugier, Tony, Tiziano, Francesco D., Lacène, Emmanuelle, Roblot, Natacha, Joshi, Vandana, Moreau, Marie Helene, Melki, Judith
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198815/
https://www.ncbi.nlm.nih.gov/pubmed/11238465

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