Tethering and tickling: a new role for the phosphatidylserine receptor

Several receptors are implicated in apoptotic cell (AC) uptake by phagocytic cells; however, their relative dominance in mammalian systems remains to be established. New studies shed light on the role of the phosphatidyl serine (PS) receptor (PSR). Ligation of PSR by PS on AC surfaces is considered...

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Detalles Bibliográficos
Autores principales: Somersan, Selin, Bhardwaj, Nina
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198851/
https://www.ncbi.nlm.nih.gov/pubmed/11706046
http://dx.doi.org/10.1083/jcb.200110066
Descripción
Sumario:Several receptors are implicated in apoptotic cell (AC) uptake by phagocytic cells; however, their relative dominance in mammalian systems remains to be established. New studies shed light on the role of the phosphatidyl serine (PS) receptor (PSR). Ligation of PSR by PS on AC surfaces is considered essential for signaling uptake of ACs that are tethered to phagocytes via other receptors.

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