Tethering and tickling: a new role for the phosphatidylserine receptor

Several receptors are implicated in apoptotic cell (AC) uptake by phagocytic cells; however, their relative dominance in mammalian systems remains to be established. New studies shed light on the role of the phosphatidyl serine (PS) receptor (PSR). Ligation of PSR by PS on AC surfaces is considered...

Descripción completa

Detalles Bibliográficos
Autores principales: Somersan, Selin, Bhardwaj, Nina
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198851/
https://www.ncbi.nlm.nih.gov/pubmed/11706046
http://dx.doi.org/10.1083/jcb.200110066
_version_ 1782148085019836416
author Somersan, Selin
Bhardwaj, Nina
author_facet Somersan, Selin
Bhardwaj, Nina
author_sort Somersan, Selin
collection PubMed
description Several receptors are implicated in apoptotic cell (AC) uptake by phagocytic cells; however, their relative dominance in mammalian systems remains to be established. New studies shed light on the role of the phosphatidyl serine (PS) receptor (PSR). Ligation of PSR by PS on AC surfaces is considered essential for signaling uptake of ACs that are tethered to phagocytes via other receptors.
format Text
id pubmed-2198851
institution National Center for Biotechnology Information
language English
publishDate 2001
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21988512008-05-01 Tethering and tickling: a new role for the phosphatidylserine receptor Somersan, Selin Bhardwaj, Nina J Cell Biol Comment Several receptors are implicated in apoptotic cell (AC) uptake by phagocytic cells; however, their relative dominance in mammalian systems remains to be established. New studies shed light on the role of the phosphatidyl serine (PS) receptor (PSR). Ligation of PSR by PS on AC surfaces is considered essential for signaling uptake of ACs that are tethered to phagocytes via other receptors. The Rockefeller University Press 2001-11-12 /pmc/articles/PMC2198851/ /pubmed/11706046 http://dx.doi.org/10.1083/jcb.200110066 Text en Copyright © 2001, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Comment
Somersan, Selin
Bhardwaj, Nina
Tethering and tickling: a new role for the phosphatidylserine receptor
title Tethering and tickling: a new role for the phosphatidylserine receptor
title_full Tethering and tickling: a new role for the phosphatidylserine receptor
title_fullStr Tethering and tickling: a new role for the phosphatidylserine receptor
title_full_unstemmed Tethering and tickling: a new role for the phosphatidylserine receptor
title_short Tethering and tickling: a new role for the phosphatidylserine receptor
title_sort tethering and tickling: a new role for the phosphatidylserine receptor
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198851/
https://www.ncbi.nlm.nih.gov/pubmed/11706046
http://dx.doi.org/10.1083/jcb.200110066
work_keys_str_mv AT somersanselin tetheringandticklinganewroleforthephosphatidylserinereceptor
AT bhardwajnina tetheringandticklinganewroleforthephosphatidylserinereceptor

Ejemplares similares