Mammalian Cells Change Volume during Mitosis

Using single cell-imaging methods we have found that the volume of adherent cells grown in culture decreases as the cells rounds when it enters mitosis. A minimal volume is reached at metaphase. Rapid volume recovery initiates before abscission as cells make the transition from metaphase to cytokine...

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Detalles Bibliográficos
Autores principales: Boucrot, Emmanuel, Kirchhausen, Tomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198941/
https://www.ncbi.nlm.nih.gov/pubmed/18213385
http://dx.doi.org/10.1371/journal.pone.0001477
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author Boucrot, Emmanuel
Kirchhausen, Tomas
author_facet Boucrot, Emmanuel
Kirchhausen, Tomas
author_sort Boucrot, Emmanuel
collection PubMed
description Using single cell-imaging methods we have found that the volume of adherent cells grown in culture decreases as the cells rounds when it enters mitosis. A minimal volume is reached at metaphase. Rapid volume recovery initiates before abscission as cells make the transition from metaphase to cytokinesis. These volume changes are simultaneous with the rapid surface area decrease and recovery observed in mitotic cells [1].
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spelling pubmed-21989412008-01-23 Mammalian Cells Change Volume during Mitosis Boucrot, Emmanuel Kirchhausen, Tomas PLoS One Research Article Using single cell-imaging methods we have found that the volume of adherent cells grown in culture decreases as the cells rounds when it enters mitosis. A minimal volume is reached at metaphase. Rapid volume recovery initiates before abscission as cells make the transition from metaphase to cytokinesis. These volume changes are simultaneous with the rapid surface area decrease and recovery observed in mitotic cells [1]. Public Library of Science 2008-01-23 /pmc/articles/PMC2198941/ /pubmed/18213385 http://dx.doi.org/10.1371/journal.pone.0001477 Text en Boucrot, Kirchhausen. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Boucrot, Emmanuel
Kirchhausen, Tomas
Mammalian Cells Change Volume during Mitosis
title Mammalian Cells Change Volume during Mitosis
title_full Mammalian Cells Change Volume during Mitosis
title_fullStr Mammalian Cells Change Volume during Mitosis
title_full_unstemmed Mammalian Cells Change Volume during Mitosis
title_short Mammalian Cells Change Volume during Mitosis
title_sort mammalian cells change volume during mitosis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198941/
https://www.ncbi.nlm.nih.gov/pubmed/18213385
http://dx.doi.org/10.1371/journal.pone.0001477
work_keys_str_mv AT boucrotemmanuel mammaliancellschangevolumeduringmitosis
AT kirchhausentomas mammaliancellschangevolumeduringmitosis

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