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Transferable Anergy: Superantigen Treatment Induces CD4(+) T Cell Tolerance That Is Reversible and Requires CD4(−)CD8(−) Cells and Interferon γ

Bacterial superantigens induce peripheral unresponsiveness in CD4(+) T cell populations that express appropriate Vβ chains. We have used Vβ3/Vα11 T cell receptor transgenic (Tg) mice and the Vβ3-specific superantigen staphylococcal enterotoxin A (SEA) to further investigate the mechanisms that contr...

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Detalles Bibliográficos
Autores principales: Cauley, Linda S., Cauley, Keith A., Shub, Fillipa, Huston, Gail, Swain, Susan L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198967/
https://www.ncbi.nlm.nih.gov/pubmed/9206999