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Itk Negatively Regulates Induction of T Cell Proliferation by CD28 Costimulation

CD28 is a cell surface molecule that mediates a costimulatory signal crucial for T cell proliferation and lymphokine production. The signal transduction mechanisms of CD28 are not well understood. Itk, a nonreceptor protein tyrosine kinase specifically expressed in T cells and mast cells, has been i...

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Detalles Bibliográficos
Autores principales:	Liao, X. Charlene, Fournier, Sylvie, Killeen, Nigel, Weiss, Arthur, Allison, James P., Littman, Dan R.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1997
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198978/ https://www.ncbi.nlm.nih.gov/pubmed/9221751

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