Self Antigens Expressed by Solid Tumors Do Not Efficiently Stimulate Naive or Activated T Cells: Implications for Immunotherapy

Induction and maintenance of cytotoxic T lymphocyte (CTL) activity specific for a primary endogenous tumor was investigated in vivo. The simian virus 40 T antigen (Tag) expressed under the control of the rat insulin promoter (RIP) induced pancreatic β-cell tumors producing insulin, causing progressi...

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Detalles Bibliográficos
Autores principales: Speiser, Daniel E., Miranda, Renata, Zakarian, Arsen, Bachmann, Martin F., McKall-Faienza, Kim, Odermatt, Bernhard, Hanahan, Douglas, Zinkernagel, Rolf M., Ohashi, Pamela S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199023/
https://www.ncbi.nlm.nih.gov/pubmed/9271580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199023/
https://www.ncbi.nlm.nih.gov/pubmed/9271580

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