Introduction of a Glycosylation Site into a Secreted Protein Provides Evidence for an Alternative Antigen Processing Pathway: Transport of Precursors of Major Histocompatability Complex Class I–Restricted Peptides from the Endoplasmic Reticulum to the Cytosol

We found that the presentation of a H-2K(d)-restricted determinant from influenza virus nucleoprotein (NP) to T cells is strictly dependent on expression of the transporter associated with antigen presentation (TAP), regardless of whether NP is expressed as a cytosolic or secreted NP (SNP). Introduc...

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Detalles Bibliográficos
Autores principales: Bačík, Igor, Snyder, Heidi Link, Antón, Luis C., Russ, Gustav, Chen, Weisan, Bennink, Jack R., Urge, Laszlo, Otvos, Laszlo, Dudkowska, Boguslawa, Eisenlohr, Laurence, Yewdell, Jonathan W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199039/
https://www.ncbi.nlm.nih.gov/pubmed/9254646

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