Cargando…

Requirement of Fas for the Development of Autoimmune Diabetes in Nonobese Diabetic Mice

Insulin-dependent diabetes mellitus (IDDM) is assumed to be a T cell–mediated autoimmune disease. To investigate the role of Fas-mediated cytotoxicity in pancreatic β cell destruction, we established nonobese diabetic (NOD)-lymphoproliferation (lpr)/lpr mice lacking Fas. Out of three genotypes, fema...

Descripción completa

Detalles Bibliográficos
Autores principales:	Itoh, Naoto, Imagawa, Akihisa, Hanafusa, Toshiaki, Waguri, Masako, Yamamoto, Koji, Iwahashi, Hiromi, Moriwaki, Makoto, Nakajima, Hiromu, Miyagawa, Junichiro, Namba, Mitsuyoshi, Makino, Susumu, Nagata, Shigekazu, Kono, Norio, Matsuzawa, Yuji
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1997
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199040/ https://www.ncbi.nlm.nih.gov/pubmed/9254659

Ejemplares similares

A Critical Role for Lymphotoxin-β Receptor in the Development of Diabetes in Nonobese Diabetic Mice
por: Ettinger, Rachel, et al.
Publicado: (2001)

Membrane Fas Ligand Kills Human Peripheral Blood T Lymphocytes, and Soluble Fas Ligand Blocks the Killing
por: Suda, Takashi, et al.
Publicado: (1997)

Reversal of Spontaneous Autoimmune Insulitis in Nonobese Diabetic Mice by Soluble Lymphotoxin Receptor
por: Wu, Qiang, et al.
Publicado: (2001)

Differences in the Contribution of the CTLA4 Gene to Susceptibility to Fulminant and Type 1A Diabetes in Japanese Patients
por: Kawasaki, Eiji, et al.
Publicado: (2008)

Hyperinsulinemia and Insulin Receptor Gene Mutation in Nonobese Healthy Subjects in Japan
por: Fujita, Shingo, et al.
Publicado: (2017)

Type 2 diabetes mellitus prevention strategy: Target and goal in Japanese men
por: Iwahashi, Hiromi, et al.
Publicado: (2016)

Class II HLA genotype in fulminant type 1 diabetes: A nationwide survey with reference to glutamic acid decarboxylase antibodies
por: Tsutsumi, Chiharu, et al.
Publicado: (2011)

Differential Induction of Apoptosis by Fas–Fas Ligand Interactions in Human Monocytes and Macrophages
por: Kiener, Peter A., et al.
Publicado: (1997)

Pathogenesis of fulminant type 1 diabetes: Genes, viruses and the immune mechanism, and usefulness of patient‐derived induced pluripotent stem cells for future research
por: Hosokawa, Yoshiya, et al.
Publicado: (2019)

Complementary and Alternative Medicine in Children with Type 1 Diabetes Mellitus
por: Haliloglu, Belma, et al.
Publicado: (2011)

Inflammatory Cytokine Profiles During Exercise in Obese, Diabetic, and Healthy Children
por: Galassetti, Pietro R., et al.
Publicado: (2011)

Endogenous insulin secretion even at a very low level contributes to the stability of blood glucose control in fulminant type 1 diabetes
por: Shibasaki, Saeko, et al.
Publicado: (2010)

Development of Inflammatory Angiogenesis by Local Stimulation of Fas In Vivo
por: Biancone, Luigi, et al.
Publicado: (1997)

T Cell Receptor Signals Enhance Susceptibility to Fas-mediated Apoptosis
por: Wong, Brian, et al.
Publicado: (1997)

Identification of Amino Acid Residues Important for Ligand Binding to Fas
por: Starling, Gary C., et al.
Publicado: (1997)

Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease
por: Landau, Anne M., et al.
Publicado: (2005)

Androgen treatment prevents diabetes in nonobese diabetic mice
Publicado: (1992)

CD40 Activation Induces Apoptosis in Cultured Human Hepatocytes via Induction of Cell Surface Fas Ligand Expression and Amplifies Fas-mediated Hepatocyte Death during Allograft Rejection
por: Afford, Simon C., et al.
Publicado: (1999)

Relationship between postprandial endotoxemia in nonobese postmenopausal women and diabetic nonobese postmenopausal women
por: Zaman, Gaffar Sarwar, et al.
Publicado: (2015)

Maximal Proliferation of Cytotoxic T Lymphocytes Requires Reverse Signaling through Fas Ligand
por: Suzuki, Ivy, et al.
Publicado: (1998)

Type 1 Diabetes and Interferon Therapy: A nationwide survey in Japan
por: Nakamura, Kan, et al.
Publicado: (2011)

Spontaneous Autoimmune Diabetes in Monoclonal T Cell Nonobese Diabetic Mice
por: Verdaguer, Joan, et al.
Publicado: (1997)

I-E+ nonobese diabetic mice develop insulitis and diabetes
Publicado: (1993)

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse
Publicado: (1987)

Possible Contribution of Taurine to Distorted Glucagon Secretion in Intra-Islet Insulin Deficiency: A Metabolome Analysis Using a Novel α-Cell Model of Insulin-Deficient Diabetes
por: Bessho, Megumi, et al.
Publicado: (2014)

Breaking self-tolerance in nonobese diabetic mice
Publicado: (1996)

Insulin tolerance test predicts the effectiveness of insulin sensitizers in japanese type 2 diabetic patients
por: Kozawa, Junji, et al.
Publicado: (2011)

Prevention of Hepatocellular Carcinoma Development Associated with Chronic Hepatitis by Anti-Fas Ligand Antibody Therapy
por: Nakamoto, Yasunari, et al.
Publicado: (2002)

Trends in maternal characteristics and perinatal outcomes among Japanese pregnant women with type 1 and type 2 diabetes from 1982 to 2020
por: Fujikawa Shingu, Kei, et al.
Publicado: (2022)

B cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency
por: Gupta, Vikas A., et al.
Publicado: (2008)

FAS Engagement Induces the Maturation of Dendritic Cells (Dcs), the Release of Interleukin (Il)-1β, and the Production of Interferon γ in the Absence of IL-12 during Dc–T Cell Cognate Interaction: A New Role for FAS Ligand in Inflammatory Responses
por: Rescigno, Maria, et al.
Publicado: (2000)

Diagnostic criteria for acute‐onset type 1 diabetes mellitus (2012): Report of the Committee of Japan Diabetes Society on the Research of Fulminant and Acute‐onset Type 1 Diabetes Mellitus
por: Kawasaki, Eiji, et al.
Publicado: (2014)

Report of the Committee of the Japan Diabetes Society on the Research of Fulminant and Acute‐onset Type 1 Diabetes Mellitus: New diagnostic criteria of fulminant type 1 diabetes mellitus (2012)
por: Imagawa, Akihisa, et al.
Publicado: (2012)

Complete loss of insulin secretion capacity in type 1A diabetes patients during long‐term follow up
por: Uno, Sae, et al.
Publicado: (2017)

Correlation of glycated albumin but not hemoglobin A(1c) with endogenous insulin secretion in fulminant type 1 diabetes mellitus
por: Koga, Masafumi, et al.
Publicado: (2010)

Predictors of postoperative bleeding after vitrectomy for vitreous hemorrhage in patients with diabetic retinopathy
por: Motoda, Saori, et al.
Publicado: (2018)

Usefulness of the insulin tolerance test in patients with type 2 diabetes receiving insulin therapy
por: Okita, Kohei, et al.
Publicado: (2013)

The Role of Macrophages in T Cell–mediated Autoimmune Diabetes in Nonobese Diabetic Mice
por: Jun, Hee-Sook, et al.
Publicado: (1999)

Extent of weight reduction necessary for minimization of diabetes risk in Japanese men with visceral fat accumulation and glycated hemoglobin of 5.6–6.4%
por: Iwahashi, Hiromi, et al.
Publicado: (2015)

Nonobese, Nonketotic Childhood-Onset Diabetes: Look for Lipodystrophies
por: Chakraborty, Partha P., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_pldr0bqtq9verav3ab37jjrrt1