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A Study of the Interferon Antiviral Mechanism: Apoptosis Activation by the 2–5A System

The 2–5A system contributes to the antiviral effect of interferons through the synthesis of 2–5A and its activation of the ribonuclease, RNase L. RNase L degrades viral and cellular RNA after activation by unique, 2′–5′ phosphodiester-linked, oligoadenylates [2–5A, (pp)p5′ A2′(P5′A2′)](n), n ⩾2. Bec...

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Detalles Bibliográficos
Autores principales:	Castelli, JoAnn C., Hassel, Bret A., Wood, Katherine A., Li, Xiao-Ling, Amemiya, Kei, Dalakas, Marinos C., Torrence, Paul F., Youle, Richard J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1997
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199051/ https://www.ncbi.nlm.nih.gov/pubmed/9294150

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