Vaccination with DNA Encoding the Immunodominant LACK Parasite Antigen Confers Protective Immunity to Mice Infected with Leishmania major

To determine whether DNA immunization could elicit protective immunity to Leishmania major in susceptible BALB/c mice, cDNA for the cloned Leishmania antigen LACK was inserted into a euykaryotic expression vector downstream to the cytomegalovirus promoter. Susceptible BALB/c mice were then vaccinate...

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Detalles Bibliográficos
Autores principales: Gurunathan, Sanjay, Sacks, David L., Brown, Daniel R., Reiner, Steven L., Charest, Hughes, Glaichenhaus, Nicolas, Seder, Robert A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199076/
https://www.ncbi.nlm.nih.gov/pubmed/9314562

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