Inhibition of T-tropic HIV Strains by Selective Antagonization of the Chemokine Receptor CXCR4

Bicyclams are a novel class of antiviral compounds that are highly potent and selective inhibitors of the replication of HIV-1 and HIV-2. Surprisingly, however, when the prototype compound AMD3100 was tested against M-tropic virus strains such as BaL, ADA, JR-CSF, and SF-162 in human peripheral bloo...

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Detalles Bibliográficos
Autores principales: Schols, Dominique, Struyf, Sofie, Damme, Jo Van, Esté, José A., Henson, Geoffrey, Clercq, Erik De
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199084/
https://www.ncbi.nlm.nih.gov/pubmed/9334378

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