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Subunit Composition of Pre–T Cell Receptor Complexes Expressed by Primary Thymocytes: CD3δ Is Physically Associated but Not Functionally Required

Maturation of immature CD4(−)CD8(−) (DN) thymocytes to the CD4(+)CD8(+) (DP) stage of development is driven by signals transduced through a pre–T cell receptor (TCR) complex, whose hallmark is a novel subunit termed pre-Tα (pTα). However, the precise role of pre-TCRs in mediating the DN to DP transi...

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Detalles Bibliográficos
Autores principales:	Berger, Marc A., Davé, Vibhuti, Rhodes, Michele R., Bosma, Gayle C., Bosma, Melvin J., Kappes, Dietmar J., Wiest, David L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1997
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199111/ https://www.ncbi.nlm.nih.gov/pubmed/9348303

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