Cargando…

CpG Oligodeoxynucleotides Act as Adjuvants that Switch on T Helper 1 (Th1) Immunity

Synthetic oligodeoxynucleotides (ODN) that contain unmethylated CpG motifs (CpG ODN) induce macrophages to secrete IL-12, which induces interferon (IFN)-γ secretion by natural killer (NK) cells. Since these cytokines can induce T helper 1 (Th1) differentiation, we examined the effects of coadministe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chu, Rose S., Targoni, Oleg S., Krieg, Arthur M., Lehmann, Paul V., Harding, Clifford V.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1997
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199137/ https://www.ncbi.nlm.nih.gov/pubmed/9362523

Ejemplares similares

CpG oligodeoxynucleotides as mucosal adjuvants
por: Iho, Sumiko, et al.
Publicado: (2015)

Immunostimulatory effects of three classes of CpG oligodeoxynucleotides on PBMC from HCV chronic carriers
por: Cooper, Curtis L, et al.
Publicado: (2008)

Dendritic Cells Are Responsible for the Capacity of CpG Oligodeoxynucleotides to Act as an Adjuvant for Protective Vaccine Immunity Against Leishmania major in Mice
por: Shah, Javeed A., et al.
Publicado: (2003)

Neonate Intestinal Immune Response to CpG Oligodeoxynucleotide Stimulation
por: Lacroix-Lamandé, Sonia, et al.
Publicado: (2009)

Systemic Administration of CpG Oligodeoxynucleotide and Levamisole as Adjuvants for Gene-Gun-Delivered Antitumor DNA Vaccines
por: Šmahel, Michal, et al.
Publicado: (2011)

Topical CpG Oligodeoxynucleotide Adjuvant Enhances the Adaptive Immune Response against Influenza A Infections
por: Cheng, Wing Ki, et al.
Publicado: (2016)

Exposure of Intestinal Epithelial Cells to Short- and Long-Chain Fructo-Oligosaccharides and CpG Oligodeoxynucleotides Enhances Peanut-Specific T Helper 1 Polarization
por: Hayen, Simone M., et al.
Publicado: (2018)

Structure-dependent immunostimulatory effect of CpG oligodeoxynucleotides and their delivery system
por: Hanagata, Nobutaka
Publicado: (2012)

Cooperative Stimulation of Dendritic Cells by Cryptococcus neoformans Mannoproteins and CpG Oligodeoxynucleotides
por: Dan, Jennifer M., et al.
Publicado: (2008)

CpG oligodeoxynucleotides potentiate the antitumor activity of anti-BST2 antibody
por: Hiramatsu, Kosuke, et al.
Publicado: (2015)

CpG oligodeoxynucleotide nanomedicines for the prophylaxis or treatment of cancers, infectious diseases, and allergies
por: Hanagata, Nobutaka
Publicado: (2017)

Synergistic oligodeoxynucleotide strongly promotes CpG-induced interleukin-6 production
por: Nigar, Shireen, et al.
Publicado: (2017)

A CpG oligodeoxynucleotide enhances the immune response to rabies vaccination in mice
por: Yu, Pengcheng, et al.
Publicado: (2018)

Lipid Nanoparticles Potentiate CpG-Oligodeoxynucleotide-Based Vaccine for Influenza Virus
por: Shirai, Seiki, et al.
Publicado: (2020)

CpG Oligodeoxynucleotides for Anticancer Monotherapy from Preclinical Stages to Clinical Trials
por: Zhang, Zhongkun, et al.
Publicado: (2021)

A Palindromic CpG-Containing Phosphodiester Oligodeoxynucleotide as a Mucosal Adjuvant Stimulates Plasmacytoid Dendritic Cell-Mediated T(H)1 Immunity
por: Maeyama, Jun-ichi, et al.
Publicado: (2014)

CpG-Containing Oligodeoxynucleotides and Freund Adjuvant in Combination with Alum Augment the Production of Monoclonal Antibodies Against Recombinant HBsAg
por: Khayyati Kohnehshahri, Mahsa, et al.
Publicado: (2022)

Inhibition of Orthotopic Genital Cancer Induced by Subcutaneous Administration of Human Papillomavirus Peptide Vaccine with CpG Oligodeoxynucleotides as an Adjuvant in Mice
por: Wang, Huan, et al.
Publicado: (2021)

CpG-Oligodeoxynucleotide Treatment Protects against Ionizing Radiation-Induced Intestine Injury
por: Zhang, Chao, et al.
Publicado: (2013)

Effects of CpG oligodeoxynucleotide 1826 on acute radiation-induced lung injury in mice
por: Li, Xuan, et al.
Publicado: (2016)

Type II natural killer T cells foster the antitumor activity of CpG-oligodeoxynucleotides
por: Zhao, Jie, et al.
Publicado: (2014)

Immunostimulatory Activities of CpG-Oligodeoxynucleotides in Teleosts: Toll-Like Receptors 9 and 21
por: Lai, Chao-Yang, et al.
Publicado: (2019)

Role of Kupffer cells in liver injury induced by CpG oligodeoxynucleotide and flucloxacillin in mice
por: Gao, Yuying, et al.
Publicado: (2020)

Anti-SARS-CoV immunity induced by a novel CpG oligodeoxynucleotide
por: Bao, Musheng, et al.
Publicado: (2006)

CpG oligodeoxynucleotides inhibit the proliferation and osteoclastic differentiation of RAW264.7 cells
por: Zheng, Yi, et al.
Publicado: (2020)

Combination of CpG Oligodeoxynucleotide and Anti-4-1BB Antibody in the Treatment of Multiple Hepatocellular Carcinoma in Mice
por: Ma, Shizhao, et al.
Publicado: (2020)

Distinct Effects of Monophosphoryl Lipid A, Oligodeoxynucleotide CpG, and Combination Adjuvants on Modulating Innate and Adaptive Immune Responses to Influenza Vaccination
por: Ko, Eun-Ju, et al.
Publicado: (2017)

Expression of Concern: A Palindromic CpG-Containing Phosphodiester Oligodeoxynucleotide as a Mucosal Adjuvant Stimulates Plasmacytoid Dendritic Cell-Mediated T(H)1 Immunity
Publicado: (2023)

CpG oligodeoxynucleotide stimulates production of anti-neutrophil cytoplasmic antibodies in ANCA associated vasculitis
por: Hurtado, Plinio R, et al.
Publicado: (2008)

Intratracheal synthetic CpG oligodeoxynucleotide causes acute lung injury with systemic inflammatory response
por: Tasaka, Sadatomo, et al.
Publicado: (2009)

Development of CpG-Oligodeoxynucleotides for Effective Activation of Rabbit TLR9 Mediated Immune Responses
por: Chuang, Tsung-Hsien, et al.
Publicado: (2014)

Chitosan-coated boron nitride nanospheres enhance delivery of CpG oligodeoxynucleotides and induction of cytokines
por: Zhang, Huijie, et al.
Publicado: (2013)

The Toll-like receptor ligand, CpG oligodeoxynucleotides, regulate proliferation and osteogenic differentiation of osteoblast
por: Yu, Wenwen, et al.
Publicado: (2020)

Structure-efficacy relationships of immunostimulatory activity of CpG-containing oligodeoxynucleotides on mouse spleen cells
por: Du, Hai-yan, et al.
Publicado: (2007)

Enhancement of the Immunostimulatory Effect of Phosphodiester CpG Oligodeoxynucleotides by an Antiparallel Guanine-Quadruplex Structural Scaffold
por: Safitri, Fika Ayu, et al.
Publicado: (2021)

Dengue-1 Envelope Protein Domain III along with PELC and CpG Oligodeoxynucleotides Synergistically Enhances Immune Responses
por: Chiang, Chen-Yi, et al.
Publicado: (2012)

Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebral Escherichia coli K1 infection
por: Ribes, Sandra, et al.
Publicado: (2014)

Effects of CpG Oligodeoxynucleotide 1826 on transforming growth factor-beta 1 and radiation-induced pulmonary fibrosis in mice
por: Li, Xuan, et al.
Publicado: (2016)

Treatment with Class A CpG Oligodeoxynucleotides in Cats with Naturally Occurring Feline Parvovirus Infection: A Prospective Study
por: Ferri, Filippo, et al.
Publicado: (2020)

Nuclease-resistant immunostimulatory phosphodiester CpG oligodeoxynucleotides as human Toll-like receptor 9 agonists
por: Meng, Wenjun, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_th7h8o2bl4fcnmen6i1au0m0q7