C-MYC–induced Apoptosis in Polycystic Kidney Disease Is Bcl-2 and p53 Independent

The SBM mouse is a unique transgenic model of polycystic kidney disease (PKD) induced by the dysregulated expression of c-myc in renal tissue. In situ hybridization analysis demonstrated intense signal for the c-myc transgene overlying tubular cystic epithelium in SBM mice. Renal proliferation index...

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Detalles Bibliográficos
Autores principales: Trudel, Marie, Lanoix, Jacqueline, Barisoni, Laura, Blouin, Marie-José, Desforges, Marc, L'Italien, Catherine, D'Agati, Vivette
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199149/
https://www.ncbi.nlm.nih.gov/pubmed/9382886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199149/
https://www.ncbi.nlm.nih.gov/pubmed/9382886

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