Cargando…

CD19-Regulated Signaling Thresholds Control Peripheral Tolerance and Autoantibody Production in B Lymphocytes

The CD19 cell surface molecule regulates signal transduction events critical for B lymphocyte development and humoral immunity. Increasing the density of CD19 expression renders B lymphocytes hyper-responsive to transmembrane signals, and transgenic mice that overexpress CD19 have increased levels o...

Descripción completa

Detalles Bibliográficos
Autores principales: Inaoki, Makoto, Sato, Shinichi, Weintraub, Bennett C., Goodnow, Christopher C., Tedder, Thomas F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199156/
https://www.ncbi.nlm.nih.gov/pubmed/9382890