Targeted Deletion of the Lipopolysaccharide (LPS)-binding Protein Gene Leads to Profound Suppression of LPS Responses Ex Vivo, whereas In Vivo Responses Remain Intact

Gram-negative bacterial lipopolysaccharide (LPS) stimulates phagocytic leukocytes by interacting with the cell surface protein CD14. Cellular responses to LPS are markedly potentiated by the LPS-binding protein (LBP), a lipid-transfer protein that binds LPS aggregates and transfers LPS monomers to C...

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Detalles Bibliográficos
Autores principales: Wurfel, Mark M., Monks, Brian G., Ingalls, Robin R., Dedrick, Russell L., Delude, Russell, Zhou, Dahua, Lamping, Norbert, Schumann, Ralf R., Thieringer, Rolf, Fenton, Matthew J., Wright, Samuel D., Golenbock, Douglas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199164/
https://www.ncbi.nlm.nih.gov/pubmed/9396775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199164/
https://www.ncbi.nlm.nih.gov/pubmed/9396775

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