Cargando…

Induction of Apoptosis of Metastatic Mammary Carcinoma Cells In Vivo by Disruption of Tumor Cell Surface CD44 Function

To understand how the hyaluronan receptor CD44 regulates tumor metastasis, the murine mammary carcinoma TA3/St, which constitutively expresses cell surface CD44, was transfected with cDNAs encoding soluble isoforms of CD44 and the transfectants (TA3sCD44) were compared with parental cells (transfect...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Qin, Toole, Bryan P., Stamenkovic, Ivan
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1997
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199167/ https://www.ncbi.nlm.nih.gov/pubmed/9396767

Ejemplares similares

Glycosylation Provides Both Stimulatory and Inhibitory Effects on Cell Surface and Soluble CD44 Binding to Hyaluronan
por: Skelton, Timothy P., et al.
Publicado: (1998)

Immunodetection of cells with a CD44+/CD24- phenotype in canine mammary neoplasms
por: Magalhães, Geórgia Modé, et al.
Publicado: (2013)

Targeted disruption of CD44 in MDAY-D2 lymphosarcoma cells has no effect on subcutaneous growth or metastatic capacity
Publicado: (1995)

Induction of Chemerin on Autophagy and Apoptosis in Dairy Cow Mammary Epithelial Cells
por: Hu, Bianhong, et al.
Publicado: (2019)

Mechanisms of osteopontin and CD44 as metastatic principles in prostate cancer cells
por: Desai, Bhavik, et al.
Publicado: (2007)

Disruption of sialic acid metabolism drives tumor growth by augmenting CD8(+) T cell apoptosis
por: Cornelissen, Lenneke A.M., et al.
Publicado: (2019)

Radiation-Induced Reprogramming of Pre-Senescent Mammary Epithelial Cells Enriches Putative CD44(+)/CD24(−/low) Stem Cell Phenotype
por: Gao, Xuefeng, et al.
Publicado: (2016)

Mammary epithelial cell phenotype disruption in vitro and in vivo through ERalpha36 overexpression
por: Thiebaut, Charlène, et al.
Publicado: (2017)

Selective killing of breast cancer cells expressing activated CD44 using CD44 ligand-coated nanoparticles in vitro and in vivo
por: Yang, Cuixia, et al.
Publicado: (2015)

Tumorigenic and Metastatic Role of CD44(−/low)/CD24(−/low) Cells in Luminal Breast Cancer
por: Vikram, Rajeev, et al.
Publicado: (2020)

C-jun Inhibits Mammary Apoptosis In Vivo
por: Katiyar, Sanjay, et al.
Publicado: (2010)

Glycosylation of CD44 is implicated in CD44-mediated cell adhesion to hyaluronan
Publicado: (1996)

CD11c depletion severely disrupts Th2 induction and development in vivo
por: Phythian-Adams, Alexander T., et al.
Publicado: (2010)

CD44 Disruption Attenuates Murine Hepatic Ischemia/Reperfusion Injury
por: Kim, Min Sung, et al.
Publicado: (2011)

Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism
por: Kaya, Gürkan, et al.
Publicado: (2006)

Proteolysis of CD44 at the cell surface controls a downstream protease network
por: Wöhner, Birte, et al.
Publicado: (2023)

Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis
por: Bishayee, Anupam, et al.
Publicado: (2016)

Interplay between Podoplanin, CD44s and CD44v in Squamous Carcinoma Cells
por: Montero-Montero, Lucía, et al.
Publicado: (2020)

Suppression by Thimerosal of Ex-Vivo CD4(+) T Cell Response to Influenza Vaccine and Induction of Apoptosis in Primary Memory T Cells
por: Loison, Emily, et al.
Publicado: (2014)

Downregulation of CD44 reduces doxorubicin resistance of CD44(+)CD24(−) breast cancer cells
por: Van Phuc, Pham, et al.
Publicado: (2011)

Growth Inhibition and Induction of Apoptosis in SHG-44 Glioma Cells by Chinese Medicine Formula “Pingliu Keli”
por: Cao, Peng, et al.
Publicado: (2011)

CD44v6‐Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells
por: Li, Linxian, et al.
Publicado: (2016)

Conditional knockout of N-Myc and STAT interactor disrupts normal mammary development and enhances metastatic ability of mammary tumors
por: Pruitt, Hawley C., et al.
Publicado: (2018)

Induced growth inhibition, cell cycle arrest and apoptosis in CD133(+)/CD44(+) prostate cancer stem cells by flavopiridol
por: SONER, BURAK CEM, et al.
Publicado: (2014)

Soluble CD44 Interacts with Intermediate Filament Protein Vimentin on Endothelial Cell Surface
por: Päll, Taavi, et al.
Publicado: (2011)

Effect of enzymic removal of cell surface constituents on metastatic colonisation potential of mouse mammary tumour cells.
por: Sargent, N. S., et al.
Publicado: (1983)

Immunohistochemical Detection of Cancer Stem Cell Related Markers CD44 and CD133 in Metastatic Colorectal Cancer Patients
por: Pitule, Pavel, et al.
Publicado: (2014)

In vivo induction of tolerance in murine CD4+ cell subsets
Publicado: (1993)

Hypoxia-Mediated ATF4 Induction Promotes Survival in Detached Conditions in Metastatic Murine Mammary Cancer Cells
por: Kiesel, Violet A., et al.
Publicado: (2022)

Effects of altering surface glycoprotein composition on metastatic colonisation potential of murine mammary tumour cells.
por: Sargent, N. S., et al.
Publicado: (1987)

Activated mouse astrocytes and T cells express similar CD44 variants. Role of CD44 in astrocyte/T cell binding
Publicado: (1993)

Metastatic Potential of Lymphoma/Leukemia Cell Lines in SCID Mice Is Closely Related to Expression of CD44
por: Kawasaki, Nobuhiro, et al.
Publicado: (1996)

Induction of tumor initiation is dependent on CD44s in c-Met(+) hepatocellular carcinoma
por: Dang, Hien, et al.
Publicado: (2015)

Hyaluronan binding function of CD44 is transiently activated on T cells during an in vivo immune response
Publicado: (1994)

In vivo monitoring of CD44(+) cancer stem-like cells by γ-irradiation in breast cancer
por: KIM, MI HYUN, et al.
Publicado: (2016)

Abrogation of Experimental Colitis Correlates with Increased Apoptosis in Mice Deficient for Cd44 Variant Exon 7 (Cd44v7)
por: Wittig, Bianca M., et al.
Publicado: (2000)

An in-silico study examining the induction of apoptosis by Cryptotanshinone in metastatic melanoma cell lines
por: Saraf, Radhika S., et al.
Publicado: (2018)

The induction of apoptosis in human mammary luminal epithelial cells by expression of activated c-neu and its abrogation by glucocorticoids.
por: Harris, R. A., et al.
Publicado: (1995)

CD44 in Differentiated Embryonic Stem Cells: Surface Expression and Transcripts Encoding Multiple Variants
por: Haegel, Hélène, et al.
Publicado: (1994)

Cosmc Disruption-Mediated Aberrant O-glycosylation Suppresses Breast Cancer Cell Growth via Impairment of CD44
por: Du, Tan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_n35kf5s7trb5s47t7mbgp22v9r