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Determinant Spreading of T Helper Cell 2 (Th2) Responses to Pancreatic Islet Autoantigens

The nature (Th1 versus Th2) and dynamics of the autoimmune response during the development of insulin-dependent diabetes mellitus (IDDM) and after immunotherapy are unclear. Here, we show in nonobese diabetic (NOD) mice that the autoreactive T cell response starts and spreads as a pure Th1 type auto...

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Detalles Bibliográficos
Autores principales:	Tian, Jide, Lehmann, Paul V., Kaufman, Daniel L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1997
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199172/ https://www.ncbi.nlm.nih.gov/pubmed/9396773

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