The High Mobility Group (Hmg) Boxes of the Nuclear Protein Hmg1 Induce Chemotaxis and Cytoskeleton Reorganization in Rat Smooth Muscle Cells

HMG1 (high mobility group 1) is a ubiquitous and abundant chromatin component. However, HMG1 can be secreted by activated macrophages and monocytes, and can act as a mediator of inflammation and endotoxic lethality. Here we document a role of extracellular HMG1 in cell migration. HMG1 (and its indiv...

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Detalles Bibliográficos
Autores principales: Degryse, Bernard, Bonaldi, Tiziana, Scaffidi, Paola, Müller, Susanne, Resnati, Massimo, Sanvito, Francesca, Arrigoni, Gianluigi, Bianchi, Marco E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199202/
https://www.ncbi.nlm.nih.gov/pubmed/11257120

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