Diacylglycerol Kinase ζ Regulates Ras Activation by a Novel Mechanism

Guanine nucleotide exchange factors (GEFs) activate Ras by facilitating its GTP binding. Ras guanyl nucleotide-releasing protein (GRP) was recently identified as a Ras GEF that has a diacylglycerol (DAG)-binding C1 domain. Its exchange factor activity is regulated by local availability of signaling...

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Detalles Bibliográficos
Autores principales: Topham, Matthew K., Prescott, Stephen M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199204/
https://www.ncbi.nlm.nih.gov/pubmed/11257115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199204/
https://www.ncbi.nlm.nih.gov/pubmed/11257115

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