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The utrophin actin-binding domain binds F-actin in two different modes: implications for the spectrin superfamily of proteins
Utrophin, like its homologue dystrophin, forms a link between the actin cytoskeleton and the extracellular matrix. We have used a new method of image analysis to reconstruct actin filaments decorated with the actin-binding domain of utrophin, which contains two calponin homology domains. We find two...
Autores principales: | Galkin, Vitold E., Orlova, Albina, VanLoock, Margaret S., Rybakova, Inna N., Ervasti, James M., Egelman, Edward H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199260/ https://www.ncbi.nlm.nih.gov/pubmed/11956227 http://dx.doi.org/10.1083/jcb.200111097 |
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