Cargando…
Conflicting Views on Chemical Carcinogenesis Arising from the Design and Evaluation of Rodent Carcinogenicity Studies
Conflicting views have been expressed frequently on assessments of human cancer risk of environmental agents based on animal carcinogenicity data; this is primarily because of uncertainties associated with extrapolations of toxicologic findings from studies in experimental animals to human circumsta...
Autores principales: | Melnick, Ronald L., Thayer, Kristina A., Bucher, John R. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199296/ https://www.ncbi.nlm.nih.gov/pubmed/18197312 http://dx.doi.org/10.1289/ehp.9989 |
Ejemplares similares
-
Carcinogenesis studies in rodents for evaluating risks associated with chemical carcinogens in aquatic food animals.
por: Huff, J, et al.
Publicado: (1991) -
Prediction of rodent nongenotoxic carcinogenesis: evaluation of biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens.
por: Elcombe, Clifford R, et al.
Publicado: (2002) -
Prediction of rodent carcinogenicity for 30 chemicals.
por: Ashby, J
Publicado: (1996) -
Predicting chemical carcinogenesis in rodents.
por: Wachsman, J T, et al.
Publicado: (1993) -
Declaring chemicals "not carcinogenic to humans" requires validation, not speculation.
por: Melnick, Ronald L, et al.
Publicado: (2003)