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Direct Evidence Revealing Structural Elements Essential for the High Binding Ability of Bisphenol A to Human Estrogen-Related Receptor-γ

BACKGROUND: Various lines of evidence have shown that bisphenol A [BPA; HO-C(6)H(4)-C(CH(3))(2)-C(6)H(4)-OH] acts as an endocrine disruptor when present in very low doses. We have recently demonstrated that BPA binds strongly to human estrogen-related receptor-γ (ERR-γ ) in a binding assay using [(3...

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Detalles Bibliográficos
Autores principales:	Okada, Hiroyuki, Tokunaga, Takatoshi, Liu, Xiaohui, Takayanagi, Sayaka, Matsushima, Ayami, Shimohigashi, Yasuyuki
Formato:	Texto
Lenguaje:	English
Publicado:	National Institute of Environmental Health Sciences 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199305/ https://www.ncbi.nlm.nih.gov/pubmed/18197296 http://dx.doi.org/10.1289/ehp.10587

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