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Intracellular Localization of Proteasomal Degradation of a Viral Antigen

To better understand proteasomal degradation of nuclear proteins and viral antigens we studied mutated forms of influenza virus nucleoprotein (NP) that misfold and are rapidly degraded by proteasomes. In the presence of proteasome inhibitors, mutated NP (dNP) accumulates in highly insoluble ubiquiti...

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Detalles Bibliográficos
Autores principales:	Antón, Luis C., Schubert, Ulrich, Bacík, Igor, Princiotta, Michael F., Wearsch, Pamela A., Gibbs, James, Day, Patricia M., Realini, Claudio, Rechsteiner, Martin C., Bennink, Jack R., Yewdell, Jonathan W.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1999
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199725/ https://www.ncbi.nlm.nih.gov/pubmed/10402464

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