Glypican-3–Deficient Mice Exhibit Developmental Overgrowth and Some of the Abnormalities Typical of Simpson-Golabi-Behmel Syndrome

Glypicans are a family of heparan sulfate proteoglycans that are linked to the cell surface through a glycosyl–phosphatidylinositol anchor. One member of this family, glypican-3 (Gpc3), is mutated in patients with the Simpson-Golabi-Behmel syndrome (SGBS). These patients display pre- and postnatal o...

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Detalles Bibliográficos
Autores principales: Cano-Gauci, Danielle F., Song, Howard H., Yang, Huiling, McKerlie, Colin, Choo, Barbara, Shi, Wen, Pullano, Rose, Piscione, Tino D., Grisaru, Silviu, Soon, Shawn, Sedlackova, Larisa, Tanswell, A. Keith, Mak, Tak W., Yeger, Herman, Lockwood, Gina A., Rosenblum, Norman D., Filmus, Jorge
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199732/
https://www.ncbi.nlm.nih.gov/pubmed/10402475

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