Kinetic Analysis of the Permeability of Human Erythrocytes to NH(4)Cl

A densimeter technique was used to make a kinetic analysis of the rate of swelling of human erythrocytes suspended in 1% NaCl following successive additions of NH(4)Cl. Two series of experiments were performed, one in the absence of and the other in the presence of 6 x 10(-4) M NaHCO(3). An analysis...

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Detalles Bibliográficos
Autor principal: Hunter, F. R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1968
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2201160/
https://www.ncbi.nlm.nih.gov/pubmed/5651773
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author Hunter, F. R.
author_facet Hunter, F. R.
author_sort Hunter, F. R.
collection PubMed
description A densimeter technique was used to make a kinetic analysis of the rate of swelling of human erythrocytes suspended in 1% NaCl following successive additions of NH(4)Cl. Two series of experiments were performed, one in the absence of and the other in the presence of 6 x 10(-4) M NaHCO(3). An analysis of the data using Widdas's equations gave a family of curves in each instance. When LeFevre's equation was used with a value of ø = 1.3 isotones, a straight line was obtained with both series of data. It is concluded that this system shows carrier kinetics.
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spelling pubmed-22011602008-04-23 Kinetic Analysis of the Permeability of Human Erythrocytes to NH(4)Cl Hunter, F. R. J Gen Physiol Article A densimeter technique was used to make a kinetic analysis of the rate of swelling of human erythrocytes suspended in 1% NaCl following successive additions of NH(4)Cl. Two series of experiments were performed, one in the absence of and the other in the presence of 6 x 10(-4) M NaHCO(3). An analysis of the data using Widdas's equations gave a family of curves in each instance. When LeFevre's equation was used with a value of ø = 1.3 isotones, a straight line was obtained with both series of data. It is concluded that this system shows carrier kinetics. The Rockefeller University Press 1968-04-01 /pmc/articles/PMC2201160/ /pubmed/5651773 Text en Copyright © 1968 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Hunter, F. R.
Kinetic Analysis of the Permeability of Human Erythrocytes to NH(4)Cl
title Kinetic Analysis of the Permeability of Human Erythrocytes to NH(4)Cl
title_full Kinetic Analysis of the Permeability of Human Erythrocytes to NH(4)Cl
title_fullStr Kinetic Analysis of the Permeability of Human Erythrocytes to NH(4)Cl
title_full_unstemmed Kinetic Analysis of the Permeability of Human Erythrocytes to NH(4)Cl
title_short Kinetic Analysis of the Permeability of Human Erythrocytes to NH(4)Cl
title_sort kinetic analysis of the permeability of human erythrocytes to nh(4)cl
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2201160/
https://www.ncbi.nlm.nih.gov/pubmed/5651773
work_keys_str_mv AT hunterfr kineticanalysisofthepermeabilityofhumanerythrocytestonh4cl

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